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PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 20ul Live Cell Imaging Key genes for eye color

SKU: 66956363288

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PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 20ul Live Cell Imaging Key genes for eye colorThis gene is a member of the type IV, cyclic AMP (cAMP) specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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Description

Key genes for eye color and hair color also map to chromosome 19

a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination

and both are required for IL23A signaling

TFE3 (transcription factor binding to IGHM enhancer 3) encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner

PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 20ul Live Cell Imaging Key genes for eye colorThis gene is a member of the type IV, cyclic AMP (cAMP) specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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